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Identifying causal regulatory variants and their target genes from the majority of non-coding disease-associated genetic loci is the main challenge in post-Genome-Wide Association Studies (GWAS) functional studies.Although chromosome conformation capture (3C) and its derivative technologies have been successfully applied to nominate putative causal
End users studying impacts and risks caused by human-induced climate change are often presented with large multi-model ensembles of climate projections whose composition and size are arbitrarily determined.An efficient and versatile method that finds a subset which maintains certain key properties from the full ensemble is needed, but very little w
Most natural IgM wedding bands in fresno antibodies are encoded by germline Ig sequences and are produced in large quantities by both mice and humans in the absence of intentional immunization.Natural IgM are reactive with many conserved epitopes, including those shared by microorganisms and autoantigens.As a result, these antibodies play important
This is a written better waters xl7000 version of the closing talk at the 22nd Los Alamos Stellar pulsation conference on wide field variability surveys.It comments on some of the issues which arise from the meeting.These include the need for attention to photometric standardization (especially in the infrared) and the somewhat controversial proble